The Curse of the Asian Glow
Hello, my name is Jennie Le, and I suffer from acetaldehyde accumulation caused by a missense polymorphism that encodes the enzyme acetaldehyde dehydrogenase (ALDH2).1 Essentially, my body does not have the enzyme that breaks down alcohol, resulting in an allergic reaction to alcoholic beverages.
Due to this condition known as alcohol flush reaction, which some of you may refer to as Asian Flush or Asian Glow, my summer tan turns into a blinding glow all over my body. My face, stomach, and thighs turn bright red, presenting my embarrassing allergic reaction for all partygoers to see. Nausea and dizziness as well as change in color caused by dilation of capillaries present itself as soon as I finish my first drink.
As a result of my explosive redness, I am embarrassed at happy hours and brunches that serve mimosas, making it difficult to keep up with my non-Asian friends when they go out. The sun is definitely not my friend since it exposes and heightens my ALDH2 deficiency for the public to see.
Take a look at the picture below, taken 10 minutes after brunch last Sunday. You have to admit; the sight isn’t pretty.
Heartburn medicine such as Zantac and Pepcid AC are have been found to reduce Asian Glow if taken 30 to 60 minutes prior to drinking alcoholic beverages.2 However, there is only anecdotal evidence since no research or studies have proved the credibility of this notion.
Fortunately, the discomfort of drinking means the decrease in likelihood that alcoholism will occur among Asian Glowers such as myself. Disulfiram is a drug for the treatment of alcoholism, which inhibits ALDH2, similar to the cause of Asian Glow; hence the connection of decreased alcoholism. 3
Currently, there is no cure to Asian Glow. I would suggest telling people you are sun-burnt, just sprinted to your current location, or hang out with friends who turn redder than you do.
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Keith Sataya
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Jennie Le
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Anonymous
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New Zealand
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David Regenold
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Jennie Le

